The Grainger College of Engineering
Materials Science & Engineering

Andrew M Smith

Andrew M Smith
Andrew M Smith
Professor
(217) 300-5638
2136 Everitt Laboratory

For More Information

Education

  • Ph.D. Bioengineering, Georgia Institute of Technology, 2008
  • B.S. Chemistry, Georgia Institute of Technology, 2002

Academic Positions

  • Affiliate Faculty, Neuroscience Program (0% FTE), University of Illinois Urbana-Champaign, 2026-Present
  • Professor, Division of Nutritional Sciences (0% FTE), University of Illinois Urbana-Champaign, 2023-Present
  • Professor of Bioengineering (100% FTE), Medicine (0% FTE), and Technology Entrepreneurship (0% FTE), University of Illinois Urbana-Champaign, 2021-Present
  • Affiliate Faculty, Personalized Nutrition Initiative (0% FTE), University of Illinois Urbana-Champaign, 2021-Present
  • Donald Biggar Willett Faculty Scholar, University of Illinois at Urbana-Champaign, 2020-Present
  • Associate Professor of Bioengineering (100% FTE), Medicine (0% FTE), and Technology Entrepreneurship (0% FTE), University of Illinois at Urbana-Champaign and Carle Illinois College of Medicine, 2018-2021
  • Associate Course Director of Hematology and Oncology, Carle Illinois College of Medicine, 2017-2023
  • Research Theme Faculty, Omics Nanotechnology for Cancer Precision Medicine (ONC-PM) (0% FTE), Carl R. Woese Institute for Genomic Biology, UIUC, 2016-Present
  • Full-Time Resident Faculty, Micro and Nanotechnology Laboratory (MNTL) (0% FTE), UIUC, 2013-Present
  • Affiliate Faculty, Department of Materials Science and Engineering (0% FTE), UIUC, 2013-Present

Course Development

  • Introduction to Quantitative Pharmacology: BIOE 450/498 Spring 2021, new

Chapters in Books

  • Ma L, Le P, Kohli M, and Smith AM. Nanomedicine in Cancer, chapter in Nanotheranostics for Cancer Applications, Springer (2019).
  • Zahid MU and Smith AM. Single-molecule imaging with quantum dots, chapter in Optical Nanoscopy and Novel Microscopy Techniques, CRC Press (2014).
  • Smith AM, and Nie SM. Semiconductor quantum dots for molecular and cellular imaging, chapter in Bionanotechnology: Global Trends, 1st Edition, CRC Press (2009).
  • Smith AM, Wen MW, Wang MD, and Nie SM. Size-minimized quantum dots for molecular and cellular imaging, chapter in Single Molecule Spectroscopy in Chemistry, Physics, and Biology, Springer (2009).
  • Rhyner MN, Smith AM, Gao XH, Mao H, Yang L, and Nie SM. Quantum dots and targeted nanoparticle probes for in vivo tumor imaging, chapter in Nanoparticles in Biomedical Imaging. Fundamental Biomedical Technologies, Vol. 102, Springer. (2007).
  • Ruan G, Agrawal A, Smith AM, Gao XH, and Nie SM. Quantum dots as fluorescent labels for molecular and cellular imaging, chapter in Reviews in Fluorescence, Springer (2006).
  • Smith AM and Nie SM. Semiconductor quantum dots for molecular and cellular imaging, chapter in Biomedical Engineering Handbook, 3rd edition, Volume 3: Tissue Engineering and Artificial Organs, CRC Press (2006).

Selected Articles in Journals

  • Lee G, Park S, Seo J, Lee W, Arogundade OH, Smith AM, Choi J, Choi H, Lim SJ. Facile Synthesis of Large-Stokes-Shift Giant CdHgSe/CdHgSeS Near-Infrared Quantum Dots via Chlorine-Mediated Ostwald Ripening. Materials Today Advances 31: 100968 (2026).
  • Xu F, Lee W, Shi K, Saha U, Cui Y, Saha U, James S, Gonzalez Medina N, Nelson ER, Smith AM. Macrophage-Targeted Quantum Dots with Short-Wave Infrared Emission for In Vivo Breast Cancer Imaging. Bioconjugate Chemistry. 37: 1987-1998 (2026).
  • Gonzalez Medina N, Cui Y, Chen D, Fayyaz M, Xu F, Mirshafeeyan M, Smith AM. Weight Loss without Food Intake Suppression through Size-Dependent Retention of Anti-Inflammatory Nanomedicines. ACS Nano. 20: 24305-24317 (2026).
  • Du L, Suarez AC, Jha V, Volety P, Lockard CA, Sutton BP, Smith AM, Ziv-Gal A, Damon BM, Bagchi IC, Wagoner Johnson A. Inflammation, Estrogen, and Matrix Remodeling in Female Reproductive Health: From Crosstalk Mechanisms to Translational Diagnostics. Biology of Reproduction. 115: 1032-1047 (2026).
  • Lee W, Hernandez Alvarez EI, Fort MJ, Xu F, Boercker JE, Schleife A, Smith AM. Core/Shell HgCdTe/HgCdSe Quantum Dots for Wave Function Engineering with Infrared Band Gaps. Journal of the American Chemical Society 148: 34592–34603 (2026).
  • Lee W, Lee SH, Nam SH, Si M-J, Baek S-W, Kim Y-H, Smith AM. Surface-Neutralized HgCdSe Quantum Dots for High-Detectivity Infrared Photodetectors. Nano Letters 26: 9250–9258 (2026).
  • Moye SL, Mittal M, Srinivasan T, Korlakunta S, Pagani CA, Dar A, Geshow O, Feist D, Zacharias LG, Li Z, James AW, Hoxhaj G, Smith AM, Gallagher KA, Mathews TP, Tower RJ, Levi B. Dietary omega-6 lipids promote postinjury aberrant bone formation in obesity. Journal of Clinical Investigation 136: e205829 (2026).
  • Kuo C-W, Nalla S, Sarkar S, Lee W, Wang L, Kohli M, Smith AM. Quantum Dot Encoding for In-Solution Single-Molecule Biomarker Counting in Metastatic Prostate Cancer. ACS Nano 20: 15949–15962 (2026).
  • Hernandez Alvarez EI, Smith AM, Schleife A. Optical properties of zincblende HgxCd1−xS and HgxCd1−xSe ternary alloys from first principles. Physical Review B, 113: 094204 (2026).
  • Applegate CC, Kang Y, Deng H, Chen D, Gonzalez Medina NY, Cui Y, Feng Y, Kuo C-W, Shahoei SH, Kim H, Vidana Gamage HE, Wallig MA, Nelson ER, Swanson KS, Smith AM. Nanomedicine Targeting PPAR in Adipose Tissue Macrophages Improves Lipid Metabolism and Obesity-Induced Metabolic Dysfunction. Science Advances, 11: eads3731 (2025).
  • Arogundade OH, Kuo C-W, Cui Y, Sarkar S, Feng Y, Kolossov VL, James S, Lee W, Smith AM. Dynamic Polymer Cross-linking Limits the Homogeneity of Compact Quantum Dots for Single-Particle Tracking. ACS Applied Materials & Interfaces, 17: 50476-50489 (2025).
  • Fayyaz M, Smith AM. Drug Depots for Obesity Targeting Metabolism, Appetite, and Inflammation. Expert Opinion on Drug Delivery, 22: 1617-1623 (2025). 
  • Feng Y, Chen D, Applegate C, Gonzalez Medina N, Kuo C-W, Arogundade OH, Wright CL, Xu F, Drnevich J, Smith AM. Nanocoding: Lipid Nanoparticle Barcoding for Multiplexed Single-Cell RNA Sequencing. ACS Nano. 19: 22079-22092 (2025).
  • Smith AM. Water-stable nanocrystals in a single step. Nature Synthesis, 4: 785–786 (2025). [Research Briefing]
  • Sarkar S, Arogundade OH, Cui Y, Hernandez Alvarez EI, Schleife A, Smith AM. Nanocrystal Synthesis with Alkoxy Reagents for Dispersion in Polar and Nonpolar Solvents. Nature Synthesis. 4: 826-835 (2025).
  • Galdino FE, Rabelo RS, Scarpa I, Yoneda JS, Consonni SR, Paes Leme AF, Smith AM, Harkiolaki M, Cardoso MB. Internalization and cellular fate of protein corona-coated nanoparticles by multimodal multi-scale microscopy. Small. 21: 2409065 (2025)
  • Zhao S, Gao K, Han H, Stenzel M, Yin B, Song H, Lawanprasert A, Nielsen JE, Sharma R, Arogundade OH, Pimcharoen, Chen Y-J, Paul A, Tuma J, Collins MG, Wylie Y, Cranick MG, Burgstone BW, Perez BS, Barron AE, Smith AM, Lee H, Wang A, Murthy N. Acid-degradable lipid nanoparticles enhance the delivery of mRNA in vivo. Nature Nanotechnology, 19: 1702-1711 (2024).
  • Applegate CA, Nelappana MB, Cui Y, Okoro G, Nielsen EA, Dovalovsky NP, Smith AM, Dobrucki IT, Dobrucki LW. Biodistribution of PET radiotracers in tumor-bearing TRAMP mice administered by retroorbital or jugular vein injections. Scientific Reports 14: 20241 (2024).
  • Entrup GP, Unadkat A, Warheit-Niemi HI, Thomas B, Gurczynski SJ, Cui Y, Smith AM, Gallagher KA, Moore BB, Singer K. Obesity Inhibits Alveolar Macrophage Responses to Pseudomonas aeruginosa Pneumonia via Upregulation of Prostaglandin E2 in Male, but Not Female, Mice. The Journal of Immunology, 213: 317-327 (2024).
  • Kolossov VL, Kanakaraju K, Sarkar S, Arogundade OH, Kuo C-W, Mara N, Smith AM. Quantum Dot-Fab′ Conjugates as Compact Immunolabels for Microtubule Imaging and Cell Classification. ACS Nano. 18: 15084-15095 (2024).
  • Lee W, Smith AM. Interdiffusion-Enhanced Cation Exchange for HgSe and HgCdSe Nanocrystals with Infrared Bandgaps. Nature Synthesis. 3: 1243-1254 (2024).
  • Wang Y, Saha U, Rubakhin SS, Roy RJ, Smith AM, Lam F. Fast, High-Resolution 1H-MRSI at 9.4T by Integrating Relaxation Enhancement and Subspace Imaging. NMR in Biomedicine. 37: e5161 (2024).
  • Lee WS, Smith AM. Nanochemistry: Magic Reactions Transform Nanoclusters. Nature Synthesis, News & Views. 2: 904-905 (2023).
  • Kuo CW, Smith AM. Digital and absolute assays for low abundance molecular biomarkers. Accounts of Chemical Research. 56: 1031-1042 (2023).
  • Martínez-Sanchez C, Bassegoda O, Deng H, Almodovar X, Ibarzabel A, de Hollanda A, de la Torre R-AMG, Blaya D, Ariño S, Jimenez N, Balibrea JM, Aguilar-Bravo B, Vallverdú J, Aguilar L, Monteroni C, Soria A, Pose E, Juanola A, Cervera M, Perez M, Hernández-Gea V, Affó S, Swanson KS, Ferrer J, Sancho-Bru P, Vidal J, Gines P, Smith AM, Graupera I, Coll M. Therapeutic targeting of adipose tissue macrophages ameliorates liver fibrosis in non-alcoholic fatty liver disease. JHEP Reports. 5: 100830 (2023).
  • Lee G, Jeong WH, Kim B, Jeon S, Smith AM, Seo J, Suzuki K, Kim J-Y, Lee H, Choi H, Chung DS, Choi J, Choi H, Lim SJ. Design and synthesis of CdHgSe/HgS/CdZnS core/multi-shell quantum dots exhibiting high-quantum-yield tissue-penetrating shortwave infrared luminescence. Small. 19: 2301161 (2023).
  • Audu CO, Melvin WJ, Joshi AD, Wolf SJ, Moon JY, Davis FM, Barrett EC, Mangum KD, Deng H, Xing W, Wasikowski R, Tsoi LC, Sharma SB, Bauer TM, Shadiow J, Corriere MA, Obi AT, Kunkel SL, Levi BS, Moore BB, Gudjonsson JE, Smith AM, Gallagher KA. Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair. Cell and Molecular Immunology. 19: 1251-1262 (2022).
  • Applegate CC, Deng H, Kleszynski BL, Cross T-WL, Konopka CJ, Dobrucki LW, Nelson ER, Wallig MA, Smith AM, Swanson KS. Impact of administration route on nanocarrier biodistribution in a murine colitis model. Journal of Experimental Nanoscience. 17: 599-616 (2022).
  • Xiong Y, Huang Q, Canady TD, Barya P, Liu S, Arogundade OH, Race CM, Che C, Wang X, Zhou L, Wang X, Kohli M, Smith AM, Cunningham BT. Photonic crystal enhanced fluorescence emission and blinking suppression for single quantum dot digital resolution biosensing. Nature Communications. 13: 4647 (2022).
  • Smith LD, Nalla S, Kohli M, Smith AM. Rapid microRNA quantification through one-pot primer-generating rolling circle amplification. Analyst, 147: 2936-2941 (2022).
  • Han Z, Vaidya RM, Arogundade OH, Ma L, Zahid MU, Sarkar S, Kuo C-W, Selvin PR, Smith AM. Structural Design of Multidentate Copolymers as Compact Quantum Dot Coatings for Live-Cell Single-Particle Imaging. Chemistry of Materials, 34: 4621-4632 (2022).
  • Deng H, Konopka CJ, Prabhu S, Sarkar S, Gonzalez Medina N, Fayyaz M, Arogundade OH, Vidana Gamage HE, Shahoei SH, Nall D, Youn Y, Dobrucka IT, Audu CO, Joshi A, Melvin WJ, Gallagher KA, Selvin PR, Nelson ER, Dobrucki LW, Swanson KS, Smith AM. Dextran-mimetic quantum dots for multiscale macrophage imaging in vivo, ex vivo, and in situ. ACS Nano, 16: 1999-2012 (2022).
  • Ma L, Geng J, Kolossov VL, Han Z, Pei Y, Lim SJ, Kilian KA, Smith AM. Antibody self-assembly maximizes cytoplasmic immunostaining accuracy of compact quantum dots. Chemistry of Materials, 33: 4877–4889 (2021).
  • Geng J, Zhang X, Prabhu S, Shahoei SH, Nelson ER, Swanson KS, Anastasio MA, Smith AM. 3D microscopy and deep learning reveal the heterogeneity of crown-like structure microenvironments in intact adipose tissue. Science Advances, 7: eabe2480 (2021).
  • Ganguli A, Mostafa A, Saavedra C, Kim Y, Le P, Faramarzi V, Feathers RW, Berger J, Ramos-Cruz KP, Adeniba O, Pagan Diaz GJ, Drnevich J, Wright CL, Hernandez AG, Lin W, Smith AM, Kosari F, Vasmatzis G, Anastasiadis PZ, Bashir R. Three-dimensional microscale hanging drop arrays with geometric control for drug screening and live tissue imaging. Science Advances, 7: eabc1323 (2021).
  • Prabhu S, Deng H, Cross T-WL, Shahoei SH, Konopka CJ, Gonzalez Medina N, Applegate CC, Wallig MA, Dobrucki LW, Nelson ER, Smith AM, Swanson KS. Nanocarriers targeting adipose macrophages increase glucocorticoid anti-inflammatory potency to ameliorate metabolic dysfunction. Biomaterials Science. 9: 506-518 (2021).
  • Liu Y, Han Z, Sarkar S, Smith AM. Fluorescence in situ hybridization with quantum dot labels in E. coli cells. Methods in Molecular Biology, 2246: 141-155 (2021).
  • Le P, Vaidya R, Smith LD, Han Z, Zahid MU, Winter J, Sarkar S, Chung HJ, Perez-Pinera P, Selvin PR, Smith AM. Optimizing quantum dot probe size for single-receptor imaging. ACS Nano, 14: 8343-8358 (2020).
  • Davis FM, Tsoi LC, Wasikowski R, denDekker A, Joshi A, Wilke C, Deng H, Wolf S, Obi A, Huang S, Billi AC, Robinson S, Lipinski J, Melvin WJ, Audu CO, Weidinger S, Kunkel SL, Smith AM, Gudjonsson JE, Moore BB, Gallagher KA. Epigenetic Regulation of the PGE2 Pathway Modulates Macrophage Phenotype in Normal and Pathologic Wound Repair. JCI Insight, 5: e138443 (2020).
  • Han Z, Sarkar S, Smith AM. Zwitterion and oligo(ethylene glycol) synergy minimizes nonspecific binding of compact quantum dots. ACS Nano , 14: 3227-3241 (2020).
  • Sarkar S, Le P, Geng J, Liu Y, Han Z, Zahid MU, Nall D, Youn Y, Selvin PR, Smith AM. Short-wave infrared quantum dots with compact sizes as molecular probes for fluorescence microscopy. Journal of the American Chemical Society, 142: 3449-3462 (2020).
  • Smith LD, Liu Y, Zahid MU, Canady TD, Wang L, Kohli M, Cunningham BT, Smith AM. High-fidelity single molecule quantification in a flow cytometer using multiparametric optical analysis. ACS Nano, 14: 2324-2335 (2020).
  • Deng H, Konopka CJ, Cross T-WL, Swanson KS, Dobrucki LW, Smith AM. Multimodal nanocarrier probes reveal superior biodistribution quantification by isotopic analysis over fluorescence. ACS Nano, 14: 509-523 (2020).
  • Le P, Chitoor SN, Tu C, Lim SJ, Smith AM. Compact quantum dots for quantitative cytology. Methods in Molecular Biology: Single Cell Metabolism 2064: 147-158 (2020).
  • Canady TD, Li N, Smith LD, Lu Y, Kohli M, Smith AM, Cunningham BT. Digital resolution detection of microRNA with single-base selectivity by photonic resonator absorption microscopy. Proceedings of the National Academy of Sciences 116: 19362-19367 (2019).
  • Le P, Lim SJ, Baculis BC, Chung HJ, Kilian KA, Smith AM. Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions. Nature Communications 10: 909 (2019).
  • Liu Y, Le P, Lim SJ, Ma L, Sarkar S, Han Z, Murphy SJ, Kosari F, Vasmatzis G, Cheville J, Smith AM. Enhanced mRNA FISH with compact quantum dots. Nature Communications 9: 4461 (2018).
  • Smith LD, Kohli M, Smith AM. Expanding the Dynamic Range of Fluorescence Assays through Single-Molecule Counting and Intensity Calibration. Journal of the American Chemical Society 140: 13904-13912 (2018).
  • Sheung JY, Ge P, Lim SJ, Lee SH, Smith AM, Selvin PR. Structural Contributions to Hydrodynamic Diameter for Quantum Dots Optimized for Live-Cell Single-Molecule Tracking. Journal of Physical Chemistry C 122: 17406-17412 (2018).
  • Zahid MU, Ma L, Lim SJ, Smith AM. Single quantum dot tracking reveals the impact of nanoparticle surface on intracellular state. Nature Communications 9:1830 (2018).
  • Ganguli A, Ornob A, Spegazzini N, Liu Y, Damhorst G, Ghonge T, Thornton B, Konopka CJ, Dobrucki LW, Clare S, Bhargava R, Smith AM, Kosari F, Bashir R. Pixelated spatial gene expression analysis from tissue. Nature Communications 9: 202 (2018).
  • Race CM, Kwon LE, Foreman MT, Huang Q, Inan H, Kesiraju S, Le P, Lim SJ, Smith AM, Zangar RC, Demirci U, Anderson KS, Cunningham BT. An automated microfluidic assay for photonic crystal enhanced detection and analysis of an antiviral antibody cancer biomarker in serum. IEEE Sensors Journal. 18: 1464-1473 (2018).
  • Lim SJ, Schleife A, Smith AM. Optical determination of crystal phase in semiconductor nanocrystals. Nature Communications. 8: 14849 (2017).
  • Mukherjee P, Lim SJ, Wrobel T, Bhargava R, Smith AM. Measuring and predicting the internal structure of semiconductor nanocrystals through Raman spectroscopy. Journal of the American Chemical Society. 138: 10887-10896 (2016).
  • Wan Y., Carlson JA, Kesler BA, Peng W, Su P, Al-Mulla SA, Lim SJ, Smith AM, Dallesasse JM, Cunningham BT. Compact characterization of liquid absorption and emission spectra using linear variable filters integrated with a CMOS imaging camera. Scientific Reports. 6: 29117 (2016).
  • Ma L, Liu T-W, Wallig MA, Dobrucki IT, Dobrucki LW, Nelson ER, Swanson KS, Smith AM. Efficient targeting of adipose tissue macrophages in obesity with polysaccharide nanocarriers. ACS Nano. 10: 6952-6962 (2016).
  • Lim SJ, Ma L, Schleife A, Smith AM. Quantum dot surface engineering: toward inert fluorophores with compact size and bright, stable emission. Coordination Chemistry Reviews. 320-321: 216-237 (2016).
  • Ma L, Tu C, Le P, Chitoor SN, Lim SJ, Zahid MU, Teng KW, Ge P, Selvin PR, Smith AM. Multidentate polymer coatings for compact and homogeneous quantum dots with efficient bioconjugation. Journal of the American Chemical Society. 138: 3382-3394 (2016).
  • Lim SJ, McDougle DR, Zahid MU, Ma L, Das A, Smith AM. Lipoprotein nanoplatelets: brightly fluorescent, zwitterionic probes with rapid cellular entry. Journal of the American Chemical Society. 138: 64-67 (2016).
  • Grolman JM, Zhang D, Smith AM, Moore JS, Kilian KA. Rapid 3D extrusion of synthetic tumor microenvironments. Advanced Materials. 27: 5512-5517 (2015).
  • Chung EY, Ochs CJ, Wang Y, Lei L, Qin Q, Smith AM, Strongin AY, Kamm R, Qi Y-X, Lu SY, Wang YX. Activatable and cell-penetrable multiplex FRET nanosensor for profiling MT1-MMP activity in single cancer cells. Nano Letters. 15: 5025-5032 (2015).
  • Lim SJ, Zahid MU, Le P, Ma L, Entenberg D, Harney AS, Condeelis J, Smith AM. Brightness-equalized quantum dots. Nature Communications. 6: 8210 (2015).
  • Dobrucki LW, Pan D, Smith AM. Multiscale imaging of nanoparticle drug delivery. Current Drug Targets. 16: 560-570 (2015).
  • Lane LA, Qian XM, Smith AM, Nie SM. Physical chemistry of nanomedicine: understanding the complex behaviors of nanoparticles in vivo. Annual Review of Physical Chemistry. 66: 521-547 (2015).
  • Wang Y, Cai E, Rosenkranz T, Ge P, Teng KW, Lim SJ, Smith AM, Chung HJ, Sachs F, Green WN, Gottlieb P, Selvin PR. Small Quantum Dots Conjugated to Nanobodies as Immunofluorescence Probes for Nanometric Microscopy. Bioconjugate Chemistry. 25: 2205-2211 (2014).
  • Lane LA, Smith AM, Lian T, Nie SM. Compact and blinking-suppressed quantum dots for single-particle tracking in live cells. Journal of Physical Chemistry B. 118: 14140-14147 (2014).
  • Cai E, Ge P, Lee SH, Jeyifous O, Wang Y, Liu Y, Wilson KM, Lim SJ, Baird MA, Stone JE, Lee KY, Davidson MW, Chung HJ, Schulten K, Smith AM, Green WN, Selvin PR. Stable small quantum dots for synaptic receptor tracking on live neurons. Angewandte Chemie International Edition. 53: 12484-12488 (2014).
  • Smith AM, Lane LA, Nie SM. Mapping the spatial distribution of charge carriers in quantum-confined heterostructures. Nature Communications. 5: 4506 (2014).
  • Lim SJ, Smith AM, Nie SM. The more exotic shapes of semiconductor nanocrystals: emerging applications in bioimaging. Current Opinion in Chemical Engineering. 4: 137-143 (2014).
  • Ma L, Kohli M, Smith AM. Nanoparticles for combination drug therapy. ACS Nano. 7: 9518-9525 (2013).
  • Kairdolf BA, Smith AM, Stokes TD, Wang MD, Young AN, Nie SM. Semiconductor quantum dots for bioimaging and biodiagnostic applications. Annual Review of Analytical Chemistry. 6: 143-162 (2013).
  • Smith AM, Nie SM. Compact quantum dots for single-molecule imaging. Journal of Visualized Experiments. 68: e4236 (2012).
  • Smith AM, Nie SM. Bright and compact alloyed quantum dots with broadly tunable near-infrared absorption and fluorescence spectra through mercury cation exchange. Journal of the American Chemical Society. 133: 24-26 (2011).
  • Smith AM, Wen MM, Nie SM. The bright future: imaging dynamic cellular events with quantum dots. Biochemist. 32: 12-17 (2010).
  • Smith AM, Nie SM. Semiconductor nanocrystals: structure, properties, and band gap engineering. Accounts of Chemical Research. 43: 190-200 (2010).
  • Smith AM, Mancini MC, Nie SM. Bioimaging: second window for in vivo imaging. Nature Nanotechnology. 4: 710-711 (2009).
  • Smith AM, Nie SM. Next-generation quantum dots.Nature Biotechnology.27: 732-733 (2009).
  • Mohs AM, Duan, HW, Kairdolf BA, Smith AM, Nie SM. Proton-resistant quantum dots: stability in gastrointestinal fluids and implications for oral delivery of nanoparticle agents. Nano Research, 2: 500-508 (2009).
  • Smith AM, Mohs AM, Nie SM. Tuning the electronic and optical properties of colloidal nanocrystals by lattice strain. Nature Nanotechnology.4: 56-63 (2009).
  • Smith AM, Nie SM. Nanocrystal synthesis in an amphibious bath: spontaneous generation of hydrophilic and hydrophobic surface coatings. Angewandte Chemie International Edition. 47: 9916-9921 (2008).
  • Kairdolf BA, Smith AM, Nie SM. One-pot synthesis, encapsulation, and solubilization of size-tuned quantum dots with amphiphilic multidentate ligands. Journal of the American Chemical Society. 130: 12866-12867 (2008).
  • Smith AM, Nie SM. Minimizing the hydrodynamic size of quantum dots with multifunctional multidentate polymer ligands. Journal of the American Chemical Society. 130: 11278-11279 (2008).
  • Mancini MC, Kairdolf BA, Smith AM, Nie SM. Oxidative quenching and degradation of polymer-encapsulated quantum dots: new insights into the long-term fate and toxicity of nanocrystals in vivo. Journal of the American Chemical Society. 130: 10836-10837 (2008).
  • Smith AM, Duan HW, Mohs AM, Nie SM. Bioconjugated quantum dots for in vivo molecular and cellular imaging. Advanced Drug Delivery Reviews. 60: 1226-1240 (2008).
  • Kairdolf BA, Mancini MC, Smith AM, Nie SM. Minimizing nonspecific cellular binding of quantum dots with hydroxyl-derivatized surface coatings. Analytical Chemistry. 80: 3029-3034 (2008).
  • Xing Y, Smith AM, Agrawal A, Ruan G, Nie SM. Molecular profiling of single cancer cells and clinical tissue specimens with semiconductor quantum dots. International Journal of Nanomedicine. 1: 473-481 (2006).
  • Smith AM, Duan HW, Rhyner MN, Ruan G, Nie SM. A systematic examination of surface coatings on the optical and chemical properties of semiconductor quantum dots. Physical Chemistry Chemical Physics. 8: 3895-3903 (2006).
  • Rhyner MN, Smith AM, Gao XH, Mao H, Yang L, Nie SM. Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging. Nanomedicine. 1: 209-217 (2006).
  • Smith AM, Dave S, Nie SM, True L, Gao XH. Multicolor quantum dots for molecular diagnostics of cancer. Expert Review of Molecular Diagnostics. 6: 231-244 (2006).
  • Smith AM, Ruan G, Rhyner MN, Nie SM. Engineering luminescent quantum dots for in vivo molecular and cellular imaging. Annals of Biomedical Engineering. 34: 3-14 (2006).
  • Smith AM, Gao XH, Nie SM. Quantum dot nanocrystals for in vivo molecular and cellular imaging. Photochemistry and Photobiology. 80: 377-385 (2004).
  • Bailey RE, Smith AM, Nie SM. Quantum dots in biology and medicine. Physica E. 25: 1-12 (2004).
  • Smith AM, Nie SM. Chemical analysis and cellular imaging with quantum dots. Analyst. 129: 672-677 (2004).

Honors

  • Fellow of the American Institute for Medical and Biological Engineering (AIMBE) (2022)
  • Donald Biggar Willett Faculty Scholar Award (2020-Present)
  • UIUC Campus Distinguished Promotion Award (2018)
  • UIUC Faculty Entrepreneurial Fellow (2016-2018)
  • IEEE EMBS Micro and Nanotechnology in Medicine Conference New Innovators Lectureship (2014)
  • NCI K99/R00 Pathway to Independence Award (2010-2015)
  • Emory University Center for Cancer Nanotechnology Excellence Distinguished Fellowship (2008-2012)
  • Whitaker Foundation Graduate Research Fellowship (2002-2006)
  • Graduation with Highest Honor, Georgia Tech (2002)
  • Lubrizol Scholarship for Excellence in Chemistry (2002)
  • Outstanding Rising Junior Award in Computer Science (1999)

Teaching Honors

  • UIUC College of Engineering Collins Award for Innovative Teaching (2019)

Research Honors

  • UIUC Grainger College of Engineering Dean's Award for Excellence in Research (2020)
  • Annals of Biomedical Engineering 2006 Best Review Paper of the Year (2007)
  • Outstanding Poster Award, Emory-Georgia Tech Frontiers of Cancer Nanotechnology Symposium (2006)
  • Photochemistry and Photobiology 2004 Best Review Paper of the Year (2005)
  • Biomedical Engineering Society Undergraduate Research Award (2001)
  • Undergraduate Research Scholar (URS), Georgia Tech/Emory, Center for the Engineering of Living Tissues (GTEC) (2000-2002)

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