MSE 474

MSE 474 - Biomaterials and Nanomedicine

Spring 2023

TitleRubricSectionCRNTypeHoursTimesDaysLocationInstructor
Biomaterials and NanomedicineMSE474A50287LCD31230 - 1350 T R  106B1 Engineering Hall Hua Wang
Yusheng Liu

Documents

Official Description

Design and synthesis of polymeric biomaterials and nanobiomaterials for their applications in drug and gene delivery. Part (1) fundamental biopolymer synthesis: functional group protection and de-protection; bioconjugation; protein pegylation and design and synthesis of natural and synthetic non-degradable and degradable polymers, hydrogels, bio-inspired materials, and stimuli responsive biomaterials. Part (2) preparation of nanomedicines for drug and gene delivery: nanofabritation of micelles, nanoparticles, protein conjugates, drug conjugates, nanoencapsulates, and polymeric vesicles; in-vitro and in-vivo small-molecule, gene, and protein delivery. Impact of the chemical structures of biopolymers on the stability, biocompatibility, toxicity, and in-vitro and in-vivo efficacy; clinical translation of the resulting nanomedicines in drug delivery. Course Information: 3 undergraduate hours. 3 graduate hours. Prerequisite: CHEM 236 or MSE 457; MCB 450.

Subject Area

  • Biomaterials